PSSD Collaborative Research

Hi Voytech, for more details read here viewtopic.php?f=10&t=2503

The European Medicines Agency (EMA) recently discussed, and is currently discussing, for the first time, persistent sexual dysfunction from SSRI / SNRI and the possibility of adding indications on drug labels. The EMA seems to have been driven in particular by the Citizen Petition written by David H...

https://www.ema.europa.eu/documents/prac-recommendation/prac-recommendations-signals-adopted-29-31-october-2018-prac-meeting_en.pdf Signal (EPITT No) Persistent sexual dysfunction after drug withdrawal (19277) Action for MAH Supplementary information requested (submission by 13 February 2019) MAH El...

all the literature up to now on pssd is here in a list http://postssrisexualdysfunction.blogspot.com/p/pssd-medical-literature.html on neuroimaging and sexual dysfunctions caused by ssri this is relevant Antidepressant-related sexual dysfunction — Perspectives from neuroimaging https://www.sciencedi...

Draft agenda for the meeting on 29-31 October 2018 Scope: Signal of persistent sexual dysfunction after drug withdrawal Action: For adoption of PRAC recommendation EPITT 19277 – Follow-up to September 2018 wait for the minutes .. in the meantime, we do not miss the chance to: - report to the pharmac...

For each with PSSD! Recently the EMA took over the discussion on the subject of PSSD and David Healy's contribution with his Citizen Petition was fundamental. It is presumed that regulators (pharmacovigilance agencies like EMA and FDA) have spent a great deal of time before taking into consideration...

Mol Neurobiol. 2017 Dec;54(10):8386-8403. doi: 10.1007/s12035-016-0304-6. Epub 2016 Dec 8. Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression. Iurescia S1, Seripa D2, Rinaldi M3. 1 Institute of Translational Pharm...

https://www.ncbi.nlm.nih.gov/pubmed/30082839 Mol Psychiatry. 2018 Aug 6. doi: 10.1038/s41380-018-0121-6. [Epub ahead of print] Variability in DNA methylation at the serotonin transporter gene promoter: epigenetic mechanism or cell-type artifact? Moore SR1, Kobor MS2. 1 Centre for Molecular Medicine ...