PSSD Collaborative Research

A forum dedicated to collaborative research into PSSD (Post-SSRI Sexual Dysfunction).

PSSD related research

Moderators: Ghost, Sonny

Post a new topic

Mark topics read • 198 topics • Page 1 of 7 • 1, 2, 3, 4, 5 ... 7

Announcements

Replies

Views

Last post

Suggested Treatment Plan
1, 2by Ghost » Sun Mar 03, 2019 8:47 pm

12 Replies

7488 Views

Last post by sulawesi
Sat Mar 09, 2019 7:31 pm

First post

Last post

Thank you so much for this very good post ghost and that you keep on working hard on the PSSD issue troughout all those years. In my opinion you understood very well which factors lead to PSSD and I would definately say that I see myself in all six risk factors and side notes that you listed. I'll...
PSSD Resources
by Ghost » Mon Jan 30, 2017 11:38 am

2 Replies

6436 Views

Last post by siebs1122
Mon Jan 30, 2017 9:56 pm

First post

Last post

Thanks for doing this Ghost, it looks like a great start.
Possible Treatments List
1, 2, 3by Ghost » Wed Dec 07, 2016 5:53 pm

26 Replies

16786 Views

Last post by Marksanchez397
Thu Oct 04, 2018 3:33 am

First post

Last post

In many other forums like “pegym”, “reboot nation”... etc there are a lot of people that have sexual dysfunction, and “casually” when I question them they say that took SSRI anytime in the past... but they don’t want to believe that their problem is PSSD and sometimes they get angry.
Forum Rules
by Ghost » Tue Nov 22, 2016 11:19 am

0 Replies

3399 Views

Last post by Ghost
Tue Nov 22, 2016 11:19 am

Topics

Replies

Views

Last post

PSSD Genome Project [Megathread]
1 ... 25, 26, 27by Ghost » Tue Apr 24, 2018 5:57 pm

261 Replies

227619 Views

Last post by Ghost
Wed Apr 17, 2019 2:50 pm

First post

Last post

@Mesolimbo When using the charts remember that: C = RED G = GREEN A = BLUE T = BLACK Heterozygotes will be combinations of the above colors. 5HTTPLR allele - rs25531 (irrelevant on 23+Me apparently - all are called C/C) - rs25532: -- 4 SNPs for rs25532 analyzed for frequency -- CC: 0.0 CG: 0.0 GG:...
PSSD research looking for patients (Enrollment extended)
1 ... 8, 9, 10by Maldoror » Fri Jul 24, 2015 4:25 pm

93 Replies

40542 Views

Last post by Johnson
Mon Nov 26, 2018 1:15 am

First post

Last post

Any update on this?
Participants wanted for PSSD study. Contact: sulawesi1@web.de
1 ... 30, 31, 32by sulawesi » Fri Feb 10, 2017 7:30 am

314 Replies

52099 Views

Last post by lw77
Thu Sep 13, 2018 11:22 am

First post

Last post

Guys but what happened to the study? Had it been done?
Ghost's Neuroscience Corner
1, 2by Ghost » Fri Sep 18, 2015 12:29 pm

10 Replies

9840 Views

Last post by Ghost
Sun Jul 29, 2018 11:22 am

First post

Last post

I've moved my educational-type postings to my website.
How does serotonin inhibit sexuality exactly?
1, 2by taarn » Fri Apr 19, 2019 6:24 am

11 Replies

438 Views

Last post by taarn
Sat Apr 20, 2019 1:28 pm

First post

Last post

Any thoughts on Tianeptine? Ive read some contradictive stuff if it really decreases serotonin. First I also found Tianeptine as interesting but I've also read contradicting stuff. But finally I thought I won't be tinkering with it. If I remember well it enhances SERT binding but can decrease SERT...
Antipsychotics, 5α-reductase inhibitors, SSRI’s, SNRI’s and TCA’s do all mess with neurosteroids!
by quagmire » Wed Apr 17, 2019 9:09 am

0 Replies

104 Views

Last post by quagmire
Wed Apr 17, 2019 9:09 am
Sexual response cycle (possible wiki)
by taarn » Sun Apr 14, 2019 2:00 pm

0 Replies

150 Views

Last post by taarn
Sun Apr 14, 2019 2:00 pm
Serotonin - Androgen Receptor Correlation (BREAKTROUGH)
by iull1k » Sun Apr 14, 2019 1:16 am

6 Replies

307 Views

Last post by Blueturtle
Sun Apr 14, 2019 9:59 am

First post

Last post

I remember reading this article, interesting. Thanks for sharing this.
Effects of Psychotherapy on 5HT1A receptor density
by paramahamsa » Fri Aug 28, 2015 12:45 pm

3 Replies

3985 Views

Last post by Blueturtle
Wed Apr 03, 2019 3:36 pm

First post

Last post

This is really fascinating. The fact that psychological talk therapy could effect the very scary real physical symptoms like ejaculatory anhedonia and genital numbness. Interesting... perhaps this impilicates 5-HT1A more in the weak genital responses? Huh. This is a super old thread but it really...
another peanutsack intro
by PsychoGenesis » Sun Mar 31, 2019 2:54 pm

4 Replies

248 Views

Last post by PsychoGenesis
Wed Apr 03, 2019 9:49 am

First post

Last post

i just got the strongest HIV coquetel available here should i take it now or will it interfere with the doxazosin?
New study reveals the epigenetic effects of Citalopram
1, 2, 3, 4, 5by nasibi » Sat Oct 20, 2018 11:56 pm

49 Replies

8737 Views

Last post by PsychoGenesis
Tue Apr 02, 2019 8:02 am

First post

Last post

hes using emitricibine/tenofovir,the green one from this site i used to get mine from here too, but seems like their site is having lots of issues lately... order from now and haven't had any problems getting it on time so does it work?
new pssd - lainfalco Intro
by lainfalco » Wed Mar 27, 2019 1:31 pm

5 Replies

426 Views

Last post by afx
Sun Mar 31, 2019 3:10 am

First post

Last post

Yes, 3 weeks is nothing really, believe me, its gonna get better soon
Fluoxetine and gut microbiota
by Ciprofloxacin » Sat Mar 16, 2019 7:18 am

6 Replies

513 Views

Last post by Halan
Sat Mar 23, 2019 4:46 pm

First post

Last post

we should focus more on gut microbiota @ghost have you seen the impact of gut microbiota on the human health? You guys should take a look at reddit.com/r/humanmicrobiome I think we should try a FMT (Fecal microbiota transplant). This has A LOT of potential. I'm willing to do it, but it's difficult...
Elevated Prolactin
1 ... 6, 7, 8by Gameclay » Tue Jan 09, 2018 2:41 pm

77 Replies

13212 Views

Last post by JK24
Sat Mar 23, 2019 1:04 am

First post

Last post

Just updating again. Still taking Pramipexole/Multivitamin/Vit-D/Zinc. Stopped Ashwagandha a few weeks ago i think. Still doing much better in the libido/Erection department still. I really think the Ashwagandha was negatively impacting my functioning. I'm getting Spontaneous erections much more...
Berberine
1 ... 8, 9, 10by Moloch » Sat Feb 07, 2015 4:29 am

93 Replies

17769 Views

Last post by TalkingAntColony
Mon Mar 11, 2019 3:09 pm

First post

Last post

Mrstaircase, Great update! Coukd you provide more details such as how you are cycling those things, dosages, and timeline of improvements?
Buspar (Buspirone)
1 ... 5, 6, 7by Ghost » Fri Aug 04, 2017 3:47 am

62 Replies

10298 Views

Last post by Ghost
Thu Mar 07, 2019 10:01 pm

First post

Last post

Several threads merged.
Cortene drug trial/Astressin B
1, 2, 3by Maxin » Wed Feb 06, 2019 1:25 pm

21 Replies

2492 Views

Last post by Maxin
Wed Mar 06, 2019 10:17 pm

First post

Last post

I also believe that our chronic fatigue is a very helpful clue in what could be behind the causes of cfs/me. That it could be a problem in the serotonergic system. I think in the last few years they have realized that chasing viruses and focusing on immune system is not getting them where they...
"Understanding the Mechanism of Antidepressant-Related Sexual Dysfunction: Inhibition of Tyrosine"
1, 2by fakeaccount » Sat Feb 09, 2019 1:57 pm

12 Replies

1372 Views

Last post by TalkingAntColony
Fri Feb 22, 2019 11:59 am
Discussion on Simonsen Systematic Review
by lw77 » Sun Feb 17, 2019 2:43 pm

1 Replies

849 Views

Last post by NeverBeenTold
Mon Feb 18, 2019 12:16 am

First post

Last post

4.3. Implications Our results suggest that patients should be informed before they are being prescribed SSRIs, that these drugs may cause long-lasting or perhaps even permanent harm on sexual function that persists after the patients have come off the drugs. Our results also provide support to...
Long-term harms from previous use of SSRIs: A systematic review. 2019
by anacleta » Sat Feb 09, 2019 4:54 am

1 Replies

790 Views

Last post by sylv
Sat Feb 09, 2019 6:18 am

First post

Last post

6 years ago I've asked my psych what are long term effects from AD use and it has greatly confused him. He gave only non-specific answers and gently changed the topic. Guess nothing has changed.
Imipramine treats citalopram PSSD in rats
1, 2by Blueturtle » Sat Dec 15, 2018 9:55 pm

13 Replies

2460 Views

Last post by Blueturtle
Fri Feb 08, 2019 11:45 pm

First post

Last post

Yes technically the rats in the clomipramine study didn’t have “post SSRI sexual dysfunction” but clomipramine does block the reuptake of serotonin and norepinephrine “10 times more affinity for serotonin then noripinephribe” Citalopram just blocks the reuptake of serotonin I don’t have access to...
Ion channel/nerve research posted on PSSDlab
by Blueturtle » Sat Feb 02, 2019 11:28 pm

3 Replies

1148 Views

Last post by Ghost
Mon Feb 04, 2019 5:01 pm

First post

Last post

Thanks for posting this! Looking over it again was good refresher!
Does anyone have anything to say about this study?
by Ciprofloxacin » Sat Feb 02, 2019 2:15 pm

2 Replies

900 Views

Last post by scripy3
Sun Feb 03, 2019 2:35 pm

First post

Last post

I had always wondered the reason why receptors don't bounce back to their normal state after antidepressants. I'm still wondering tbh. How about immune system? There is relation immune system - 5-ht sytem To some this can be true, maybe to some it's hormone The studies are random. but have a look
GABA A3/4/5, inflammation and mitochondria
1, 2, 3by Ciprofloxacin » Wed Sep 05, 2018 12:14 am

24 Replies

5525 Views

Last post by Maxin
Sat Feb 02, 2019 3:42 pm

First post

Last post

Yes of course. I first tried dexamethasone years ago. I was a professional dancer and had to get through a performance, so docs gave me a weeks worth as I was having such bad fatigue. This was a few months after stopping ssri. It did help but he only prescribed for a week. But this led to me to...
"Heart rate variability biofeedback increases sexual arousal" 2018
by anacleta » Thu Jan 10, 2019 6:27 am

0 Replies

810 Views

Last post by anacleta
Thu Jan 10, 2019 6:27 am
8-oh-dpat treats clomipramine PSSD in rats
by Blueturtle » Mon Dec 24, 2018 8:33 pm

4 Replies

1417 Views

Last post by Blueturtle
Tue Jan 08, 2019 6:24 pm

First post

Last post

Yeah, it’s clear that a giant pinch of salt should be taken with any animal study trying to link it to potential human treatments. I just posted it because it’s another hopeful sign that we can help ourselves with SOMETHING with the fact that sexual deficits in animals from early serotonin drugs...
Alpha:Beta activity in PSSD.
1, 2by JayR » Mon Jan 07, 2019 10:55 am

10 Replies

1529 Views

Last post by JayR
Tue Jan 08, 2019 2:22 pm

First post

Last post

@jayR what about being good enough and sharing ur pssd recovery if u rly had it? whats ur curently on? -yohimbe -prasozin -cialis -dextroamphetamine -metergoline u use these or none of this? sry but i look u as another internet prophet until u give the community something realistic and sincere...
"Pharmacogenetics of glutamate system genes and SSRI-associated sexual dysfunction" 2012
by anacleta » Sat Sep 08, 2018 11:34 pm

3 Replies

3174 Views

Last post by JayR
Tue Jan 08, 2019 1:51 pm

First post

Last post

Mine is normal = no increased/decreased risk for SSRI-induced Sexual Dysfunction.
"Efficacy of testosterone combined with a PDE5 inhibitor and testosterone combined with a .." 2015
by anacleta » Sat Sep 08, 2018 11:39 pm

1 Replies

2969 Views

Last post by JayR
Tue Jan 08, 2019 1:50 pm

First post

Last post

Yeah, or PT-141. It works for Women pretty well too!!!
Pramipexole - D2, L-arginine and PDE-I
by magnilo » Wed Nov 14, 2018 2:04 am

1 Replies

1238 Views

Last post by JayR
Tue Jan 08, 2019 1:47 pm

First post

Last post

I've found this study and to be honest im fairly puzzled, my knowledge is very superficial and mostly limited to SE/NE/DA receptors, so id appreciate if someone with a more in depth knowledge could make some sense out of this the following study investigate the effects of coadministration of...

Post a new topic

Mark topics read • 198 topics • Page 1 of 7 • 1, 2, 3, 4, 5 ... 7

Return to Board index

Jump to:

Who is online

Users browsing this forum: No registered users and 1 guest

Icon Legend

New posts	No new posts	Announcement
New posts [ Popular ]	No new posts [ Popular ]	Sticky
New posts [ Locked ]	No new posts [ Locked ]	Moved topic

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum