Success with Tianeptine and Ashwagandha

[Gameclay]

Hello everyone, i am a long time lurker and decided I should make an account and post about the success I have been having with this combination. Because we all know how few and far between positive stories about this shitty condition are. Hopefully this can help in some way.

I am a 23 year old male and I have been suffering for a little over a year with PSSD from 5 days of 5-HTP use. I was taking it with Rhodiola and EGCG which is green tea extract. I lost my libido and could barely get an erection, and my semen became much more clear and watery when it used to be thick and pearly white before this. This persisted after I stopped taking it.

I have had windows and waves of full functioning once in a great while but for the most part I have had very poor functioning and no libido. I also have PSSD in the form of pleasureless orgasm from 3 months of prozac in 2015, that did not effect sexual functioning or libido though.

I have found that taking these supplements have restored my sexual functioning greatly. My libido is much better. I can get an erection from thoughts and watching porn. And my erection does not die out on me. Also the tianeptine gives me lots of pleasure back into my orgasms.

What I'm taking every day:

Multivitamin every morning

10,000 IU vitamin D every morning

Ashwagandha 400mg every morning, sometimes 800mg (root powder. NOT EXTRACT. Organic India brand) this must be increasing testosterone and lowering cortisol as stated in the medical studies. Makes my muscles look pumped up without working out much and makes me look leaner. Also makes my erections much Fuller. I believe Ashwagandha also reverses opioid tolerance and allows me to take low doses of Tianeptine without having to increase all the time. Takes around a week of consistent use to see results.

Tianeptine sodium - one 70-90mg dose after work every day. ( Bought from newmind) YES I take enough to get me high. Tianeptine works on μ-opioid receptors and will get you high like a painkiller if you take a high enough dose. This seems to greatly help my erectile function and libido. Sometimes after it kicks in I will start to get a boner without thinking about anything. It' also works greatly as an antidepressant and the afterglow I get from this one dose lasts me around 24 hours. If you plan to try this please only start with 30mg or so doses to figure out what works for you. Taking too much when you have no tolerance will give you horrible nausea and you'll have to lay down for a long time.


Moclobemide 150mg in morning and 150mg after work at 4pm. I have only been taking this for 2 weeks and can't tell if it's doing anything. I bought this from Brandmedicines. com


The two biggest factors in this combo I think are the Tianeptine and Ashwagandha. Both of these have an effect on the HPA axis it seems.

The novel antidepressant, tianeptine, reduces stress-evoked stimulation of the hypotalamo-pituitary-adrenal axes


http://www.sciencedirect.com/science/ar ... 999190284W


During one randomized, double-blind, placebo-controlled trial involving 64 individuals with a history of chronic stress, those taking 300 mg BID of a high-concentration, full-spectrum ashwagandha extract for 60 days showed significantly reduced (p<0.0001) stress-assessment scores. Serum cortisol levels were also substantially lower (p=0.0006) in the ashwagandha group compared to those in the placebo group.30
http://ndnr.com/anxietydepressionmental ... -hpa-axis/


I personally think this problem has something to do with hormones rather than brain neurons, but who knows.. I had my testosterone (free and total) and thyroid checked in April when I wasn't taking anything and both were in range, but I had no libido or erection capability. Hopefully some of you can try these and get some relief!

[Jaxx]

Never heard of the combination of tianeptine and moclobemide. Is this medically supervised? Tianeptide is far from novel btw, the article is from 1991...
Thanks for posting anyway, good to hear it helps you!

[Gameclay]

No it's not medically supervised. Everything i'm taking i bought on the internet and shipped to my house.

[fema4psyciatrists]

I had a dream ages ago as I metaphorically cried myself too sleep on my the floor without covers. A metaphorical ancient man (appeared as a big boned native American man) next to me told me that I was too traumatized to be able to handle this and the best thing for me is if I fall asleep, and he informed me he I needed Ashgwandwa and would rub it on in a mixture paste onto I think my feet as I fell asleep. I have already caused most further injuries by 'trying stuff' and been almost poisoned to death by a 'gay' 'friend' inbetween as well so I have never tried Ashgwanda. However it is a popular herb as well as a mild one so I would have thought if it had worked someone would have found that out by now in addition how could something so mild and popular work to fix this...

Where do you get your Ashgwanda from? Do you believe it would work on it's own? How long till you felt its effects?

Have you ever seen if the improvements remain if you come off it?

can't wait to hear back. Thanks

[Gameclay]

I had a dream ages ago as I metaphorically cried myself too sleep on my the floor without covers. A metaphorical ancient man (appeared as a big boned native American man) next to me told me that I was too traumatized to be able to handle this and the best thing for me is if I fall asleep, and he informed me he I needed Ashgwandwa and would rub it on in a mixture paste onto I think my feet as I fell asleep. I have already caused most further injuries by 'trying stuff' and been almost poisoned to death by a 'gay' 'friend' inbetween as well so I have never tried Ashgwanda. However it is a popular herb as well as a mild one so I would have thought if it had worked someone would have found that out by now in addition how could something so mild and popular work to fix this...

Where do you get your Ashgwanda from? Do you believe it would work on it's own? How long till you felt its effects?

Have you ever seen if the improvements remain if you come off it?

can't wait to hear back. Thanks

i buy it off amazon usually but a vitamin store would probably sell it too.
https://www.amazon.com/Organic-India-As ... india&th=1

Ashwagandha is something i've been using for quite a few years now even before i got PSSD. It would give me the biggest sex drive ever and i'd easily be able to go 4-5x a day. It's effects are truly remarkable. It seems to acts like a steroid of some sort.... Even my Cardiovascular functioning is greatly enhanced and when playing sports like hockey i barely get tired at all and am able to keep going without much effort. When i haven't been taking it for a week or so the effects seem to fade.

i'd say that now with PSSD the Ashwagandha helps somewhat but with the addition of Tianeptine all systems are go... Even yesterday i masturbated like 3 times without issue. And twice today!

[Ghost]

Welcome to the forum and it's great to hear that it's working for you! I'm happy to hear it! It's weird how 5-HTP can cause this also. I took 5-HTP at the same time as Lexapro, so I never can truely work out the damage that each caused alone (also was on Trazodone and Ativan - must have fucked my brain pretty good those 4 days). Probably one of the stupidest things ever, but we all were a bit more naive before this BS. Hindsight is 20/20.

Ashwagandha is high up on my "To Try" list. Vitamin D is massive and I think it helps me also. Something to think about is that you might want to be careful with calcium levels. I don't think that 10k/day will be enough to be a huge problem, but it's something to keep an eye on.

I think Cortisol is involved for sure. I should re-test my levels. Before it wasn't too high, but was high. Licorice comes to mind as another important modulator of Cortisol.

Anyways, glad to have you here and hopefully you'll keep us posted w/updates.

[Gameclay]

Welcome to the forum and it's great to hear that it's working for you! I'm happy to hear it! It's weird how 5-HTP can cause this also. I took 5-HTP at the same time as Lexapro, so I never can truely work out the damage that each caused alone (also was on Trazodone and Ativan - must have fucked my brain pretty good those 4 days). Probably one of the stupidest things ever, but we all were a bit more naive before this BS. Hindsight is 20/20.

Ashwagandha is high up on my "To Try" list. Vitamin D is massive and I think it helps me also. Something to think about is that you might want to be careful with calcium levels. I don't think that 10k/day will be enough to be a huge problem, but it's something to keep an eye on.

I think Cortisol is involved for sure. I should re-test my levels. Before it wasn't too high, but was high. Licorice comes to mind as another important modulator of Cortisol.

Anyways, glad to have you here and hopefully you'll keep us posted w/updates.

i also think cortisol is involved, Tianeptine and ashwagandha both lower it..

[Gameclay]

(edited double post)

[bhasski]

I have been taking Ashwagandha powder for almost 4 months. But don't find any effect on PSSD.
I though take it with licorice root powder.
Not tried tianeptine as I am scared of pharma bullshit.

[Gameclay]

I have been taking Ashwagandha powder for almost 4 months. But don't find any effect on PSSD.
I though take it with licorice root powder.
Not tried tianeptine as I am scared of pharma bullshit.

What brand do you take? I've been taking organic India for like 3 years, I tried KSM-66 for a week and all it did was make me an angry asshole with no benefits whatsoever... as far as Tianeptine goes, it doesn't have any negative sexual effects so I'd say the only thing one would have to be careful with is to have self control. I never thought it would do what it has for me but I'm glad I found it!