PSSD Collaborative Research

Hi guys. Has anyone here had long term success with PDE5 inhibitors? What I mean by this is has somebody here taken viagra / cialis regularly over a long period of time and found that they have improved their endothelial function?

I recently took some generic cialis before bed and it worked amazingly. The effects lasted 3-4 days and that whole week my erections were noticeably better, even after the cialis had worn off. I’m unsure whether I should be taking cialis consistently, say 1-2 times per week to try replicate this success or would it be better to just save it for when I’m going to have sex in order to prevent tolerance. Any advice is appreciated.

Also huge thanks to Mesolimbo because cialis had stopped working for me for a long time, but I read something he wrote about l-arginine and l-citrulline so I have been taking both those supplements every day for the last few weeks and when I tried the cialis it finally worked again.

Tadalafil Vardenafil Avanafil Sildenafil
that's the only hope. Use them in a cycle to avoid tolerance. Let me know what you have the best effects with. I can't live without Viagra. Even after discontinuation, erection and a little libido improve.
I think it's a good way to test them all.

I developed rapid tolerance to viagra and vardenafil. Cialis has the opposite effect and works better the longer you use it.
If you want to downregulate pde5 you could take horny goat weed or berberine. Takes several weeks to take effect but it works.

i dont know about the long term but i have recently tried 10mg as suggested by my a new doc instead of the usual 5mg
the quality of the result was FAR superior and i have the impression something "snapped". My normal erections (as in, without pdei) feel slightly firmer now. I will try again in a while