According to its Wikipedia page, the drug has been reported to be a serotonin (including 5HT1a), dopamine, and epinephrine agonist. I have read through some studies that suggest it has a ht1a agonistic property to it. I will admit that I don't understand the articles as I am not a scientist. But the articles should certainly provide a good discussion for those who do understand them. Read them, but don't take these studies as any sort of hope for us.
http://en.wikipedia.org/wiki/Ergotamine
http://www.ncbi.nlm.nih.gov/pubmed/9778659
http://europepmc.org/abstract/med/9009470
The vasoconstriction this drug causes is definitely something to watch out for as none of us want gangrene.
Let me know what you think. Let's have a discussion.





