Long Term Treatment - r OP

[Moloch]

r on Tue Oct 21, 2014 10:21 pm

So I've decided to stop fucking around and, while working with psychiatrists for prescription medicine, do routines of things available over the counter that have potential for permanent upregulation. I'll be doing three month cycles with them, starting with Meriva, which Sonny said helped permanently. I'm also going to incorporate berbirine and icariin into my routine, based on recent positive results from it (and hopefully downregulate PDE-5 receptors in the process). I'm going to keep track of progress in this thread for the duration of it. I've been a bit inactive on the forums, but just with posting, I'm consistently lurking.

What I'm already taking every day: Vyvanse, Nicazel (which contains a mixture of nicotinamide, azelaic acid, quercetin, curcumin, pyidoxine, zinc, copper, and folic acid. I think the zinc and curcumin might explain why it had a positive effect on my pssd, especially with regards to libido), huperzine a, Choline, and Vitamin D . I've gotten lazy with taking it, so starting again will help.

This is the stuff I'm definitely taking, and they might overlap a bit in the time period of when i can take it, but i'll probably take them in this order. Not sure on doses, if anyone has suggestions I'd love to hear them.

Meriva SR (Curcumin)
Mucuna Pruriens
Ginkgo Biloba (take indefinitely, or at least through the inositol, not sure about it's potential efficacy)
Bacopa Monnieri
Ginseng routine (probably won't do anything, but routines in high doses have had efficacy in 16 week trials for ED, so it's worth a shot).
Piracetam
Inositol (During the summer, so the ADHD effects don't really matter).

Through the Piracetam, this should take about nine months or so, with another two in the summer for the inositol. Most of these things have been indicated by studies to provide upregulation of serotonin receptors, or other things that have been affected by pssd. and have I'm probably going to talk to my doctor about getting a yohimbine Hcl prescription, and I'll try other things as they come up/after this routine/etc.

Other things I'm considering:

More vitamins/minerals/etc (could probably use them anyway, I should be taking magnesium and vitamin C supplements anyway)
Gotu Kola (potential to upregulate alpha-2 adrenergic receptors, might take concurrently with bacopa)
Muira Puama, catuaba bark, ashwagandha (useful for upregulation of GABA, I believe. Some of them are at least, I might be getting confused. Muira has some effects on adrenergic preceptors too, I believe).
L-Carnitine with Alpha Lipoic acid (upregulation of androgen receptors)
L-Theanine (would probably take as a nootropic regardless)
Forskolin
Fenugreek (I've heard some positives about it but doubt it'd do too much)
Licorice root (I highly doubt that it'd help me, but if I'm doing a comprehensive routine like this in an attempt to fix things, I might as well do it as there's claims of its efficacy
Tribulus (I'm hesitant, because I've had problems with acne before that I've gotten under control and really don't want them to come back)

If anyone has advice for dosage on this, or recommendations for/against supplementation, I'd love to hear them. Ordering Meriva tonight, hopefully.

[Moloch]

forexworld12 on Tue Oct 21, 2014 11:22 pm

All those are great Idea,!Ginko blocks S - receptor T4 i guess , Inositol both upregulates dopamine and serotonin, Zinc,Magnesium & curcumin all upregulate Dopamine receptors permanent effect so it has the potential to alleviate Ahnedonia/depression,PSSD and Increase mood, By doing this you have much higher chance of success . I am totally broke at the moment but these stuff are in the A list of my supplementation. My ashwagandha,bacopa and Valerian are arriving in 3 days. Piracetam as I have read can exaggerate ahnedonia, and can lower libido too but it could be different for PSSD people . area doesn't recommend berbirine and icariin for me at the moment so i'm keeping that at a hold. The only thing i won't try is L-theanine and pircatepam !

[Moloch]

r on Tue Oct 21, 2014 11:36 pm

forexworld12 wrote:
All those are great Idea,!Ginko blocks S - receptor T4 i guess , Inositol both upregulates dopamine and serotonin, Zinc,Magnesium & curcumin all upregulate Dopamine receptors permanent effect so it has the potential to alleviate Ahnedonia/depression,PSSD and Increase mood, By doing this you have much higher chance of success . I am totally broke at the moment but these stuff are in the A list of my supplementation. My ashwagandha,bacopa and Valerian are arriving in 3 days. Piracetam as I have read can exaggerate ahnedonia, and can lower libido too but it could be different for PSSD people . area doesn't recommend berbirine and icariin for me at the moment so i'm keeping that at a hold. The only thing i won't try is L-theanine and pircatepam !

Piracetam has a pretty good track record for PSSD, as well as stimulating neurogenesis in general (which would work well in me I think. I'm still young and have a lot of potential neuroplasticity).

Zinc was great for me, and I took it accidentally (Nicazel was prescribed for acne by a dermatologist). I attribute my libido being back to 100% to taking hyperdoses of zinc, which nicazel provides.

I've noticed that a lot of the stuff Sonny tries and works for him people say don't work for them. He has done routines of things to partially upregulate receptors, while others haven't. Maybe the lack of permanent treatment makes acute treatment less effective? Just musing on the subject.

Nevertheless, I'm going to work on more permanent treatment for the next year or so. We'll see if any new things pop up, or if it honestly doesn't help at all. Other than Yohimbine, I don't see myself trying new prescription medications for the next year (other than PDE-5 inhibitors, if I can get ahold of them). If in a year this routine, combined with time and the continued dosing of ropinirole+choline+huperzine A and other vitamins hasn't helped to a point where I'm able to function decently with the aid of Buspar/Yohimbine/whatever, I'll start looking at treatments such as Trazodone, etc.

[Moloch]

forexworld12 on Tue Oct 21, 2014 11:53 pm

Funny I just posted about it .....I am sure What sonny took before did upregulated his receptors in the meantime so that is the reason why he reponds well to stuff and that is the reason why some don't respond or if they respond the effects fade away in a week...how will we respond when the receptor itself doesn't and is weak. I am confident that is one of the main why we suffer from ahnedonia,vision problems dliated pupil etc because of the desentisization .! zinc is really good.. the fact is restored your libido 100% is only more and more clear about its upregulation potential as well as increasing it but cycle it every few weeks..
piractepam has mixed reviews .. Sulbutiamine is better , NS1-189 does the same thing but its amazing for depression as most people report that, don't underestimate stablon when it comes to upregulation, increasing firing rate rapidly increasing concentration of dopamine and also increasing density ... ...BPAP has the potential for a cure, Bromantane is also good , but way better than that is phenylpiracetam in the PSSD department ...and even better is 9-methyl-beta-carboline. There are lots of interesting chemical present out there today by which we can completely treat PSSD like how sonny does it but ultimately I'm aiming for a permanent cure. it's hard but with more and more enlightment its possible !

[Moloch]

Trez123 on Wed Oct 22, 2014 5:41 am

My input is usually not appreciated around here but I would like to say that unless taking a pile of pills/ capsules isn't an issue for you, that if you can obtain powder it is usually more efficacious. I only use a few of what you plan to and only just started choline today. I have taken Mucuna pruriens for a lot of the time I've had PSSD which is almost 4 years. The powder works a lot better for me. I take 1.5 teaspoons of it every day. Mine is 15% L-dopa. I can't take capsules/ pills too much cause it triggers my personality disorder. I kind of wish I could find a higher L-dopa % but its hard unless you have a good income, and I don't. I take zinc too, in ZMA form. I'm yet to find a source of huperzine A that I can afford. I also take tyrosine but its not really useful for sexual functioning besides allowing phenylethylamine chains be more active, which in turn slightly increases dopamine but also adrenaline so if too much is taken it can be vasoconstrictive. If you have a test level within normal range mucuna pruriens will boost it somewhat. It doesn't for me cause I have to take TRT. It also increases HGH and decreases prolactin which may increase sexual functioning. It allows me to have erections but by what mechanism of action I'm unsure. I might add that if you have genital anesthesia it could desensitize you more :/ It does for me, best way to describe it is that what feels good to a guy without PSSD isn't there and I might as well be touching my arm on a good day and a rock on bad days. Excuse my stupidity, but curcumin is the active ingredient in tumeric, right? And what is Bacopa monnieri? I am trying new stuff for me cause I'm not improving and haven't since starting TRT a year ago. I hate knowing men my age (I'm 19) are pretty much at sexual prime and I only get one erection a day, have severely delayed orgasm, ejaculatory anhedonia, genital anesthesia and sometimes painful ejaculation. I have virtually no libido and can't be aroused at all unless I do it myself. Maybe I have seen a bit of improvement in visual stimulation and sexual thinking but not much really. It took about 3 months for mucuna pruriens to give me one erection each day in conjuction with TRT and maybe ZMA (not sure about ZMA?) Most times I need to manually stimulate to get it but rarely I don't have to and it just happens. Small windows perhaps. Its good to take mucuna pruriens with green tea and on an empty stomach too (I drink regular green tea, 2 tea bags) and stir it in it and drink. The catechins in green tea help the L-dopa cross the blood- brain barrier. But some people find green tea extract better. Sorry. I talk too much. I was just trying to give my experience really, sorry if I am annoying. You can tell me to shut up if you like

[Moloch]

forexworld12 on Wed Oct 22, 2014 5:56 am

Oh don't worry about it I'm a year older to you so i can completely understand ...Your input is appreciated . feel free to comment anywhere without hesitation - we are all in this together .. It's just that when you came you were very arrogant and didn't want to listen to any logical conclusion coming from noobs like me to exp people like sonny .. so i hope that is resolved..I have Libido.sensation and orgasm problem ..I can orgasm quickly(premature) but there's no feeling in it.. ! I don't have erection issues so i can't comment on that.. I can vouch for powder stuff working better than the pills !
yes curcumin is that is which in tumeric .. L-DOPA or mucuna isn't really an option until others stuff are fixed ! I think you should change your endro first because if i am not wrong it's messed up but your doctor doesn't do anything about it .. TRT or testo problem is only a small part of the problem .. so even with high testo it isn't going to help much when your brain is fucked up.. what medication are you on currently ? do you go to gym excersize ? how is your diet ? all these are gonna play a big role in the road to recovery ...

[Moloch]

Trez123 on Wed Oct 22, 2014 6:21 am

My doctor is a twit lol. She isn't an endo, just a general practitioner. I originally went to an endo but he was too expensive for me. It would have been better but bills need to be paid!! Lol. My hormones are fucked up, yes. I'm getting my next blood test in a couple weeks to see how fucked they are again cause that's the end of my T cycle then. Last time my doctor said my estradiol and progesterone and also prolactin were too high!! Like really she said my prolactin is almost as high as a girl having a baby and she said well its funny you still have male genitals with your estradiol level and she said she doesn't know what progesterone is!! I said so yeah are you gonna do anything about those or what? She said well I'm hoping your TRT will lower those. I said really, are you serious? Test will not lower those at all, in fact test if its normal will aromatize and turn into estrogen in my liver you know. She said that's silly of course test is just test and doesn't turn into estrogen. I am dumbfounded by her really. I take an OTC aromatase inhibitor, can't remember the name. And I do exercise, walking for 45 mins each day (sometimes more). My diet is probably shitty though cause I binge eat but just once a day and only nuts and fish usually. I don't eat junk foods. Only fish and nuts, rice and potatoes baked in the oven. I sometimes eat eggs. I am lactose intolerant so no dairy. Oh and green vegetables too. Lots of water. I only drink that and tea. I drink chamomile tea a lot as well as green tea. My test level isn't high, its in the middle, usually like 513-530. I asked my doctor why can't I take my injection more frequently to make that a bit higher and she said cause if you do it will cost more cause I'll have to give you a private script instead of a public one which cause I'm on disability I get it for 6 dollars with my pension card if I only take it every 10 weeks like the authority public script says its for

[Moloch]

Trez123 on Wed Oct 22, 2014 6:58 am

I really don't know if my prolactin level is as high as she says cause I don't lactate at all. Never have. My refractory period is very long (about a day) though and prolactin contributes to that. My doctor really has no clue what she is doing at all and I try to find another one but can't. Not many here. I just try to find herbs and supplements to try fix it all some!! What else can I do really. Next one I'm trying is shilajit cause Area suggested it to me. Trying to save money for it and also cissus to lower my cortisol level. I wish yohimbine was legal where I live cause that blocks all the serotonin receptors that might help me, but its not allowed here. I wonder if there is anything similar to it

[Moloch]

r on Wed Oct 22, 2014 7:42 am

Hearing these things, along with some further research, is making me reconsider taking mucuna. I don't have a huge need for dopamine supplementation as I take a dopamine agonist twice daily, as well as a CNS stimulant. I'll probably go straight into the bacopa after finishing the circumin. And yes, circumin is the active ingredient in turmeric. I'd love if Sonny could give me some feedback on this. I'm probably going to see my psychiatrist next month, and discuss this with him.

[Moloch]

Trez123 on Wed Oct 22, 2014 8:32 am

If you already take DAs then mucuna pruriens won't do much really. If IT had the choice to take a DA I would cause so far herbs are doing very little for me. However my serotonin is still too desensitized and high on the postsynaptic side. That is probably why I've lacked improvement. Hopefully shilajit might help that. I read about bacopa and that might make my choline more useful without huperzine A cause it does the same thing. Area comes by every so often. He is very useful. Its lucky that you have a psych that works with your needs instead of suggesting garbage. It is very rare. Sometimes I honestly think they went to medical school just to fuck with people's heads even more than most people with mental disorders suffer on our own. Mine is an asshole. He actually says to me that it would be funny if he pissed me off and I lost control in front of him cause he enjoys insulting people with my personality disorder. I walked out of his office of course