DXM/naltrexone trial - Psychogenesis

[PsychoGenesis]

started on sunday 24/11/2019
dose dxm 300mg naltrexone 25mg

day 1 - took dxm and naltrexone at the same time, I'm very dissociated
day 2 - same
day 3 - getting less dissociation, prolly because nalt is building up and inhibiting the dxm>dxo conversion(cyp2d6)> https://www.ncbi.nlm.nih.gov/m/pubmed/29744741/
http://media.corporate-ir.net/media_fil ... hl_5_3.pdf


and how do i know it's not tolerance to NMDA antagonism? because before starting this trial i tested 300mg + a low dose of naltrexone (5mg) and it blocked "dxm" effects

day 4 - very disphoric the moment when i wake up but then it subsides

day 5 - same, no dissociation even tho i dosed DXM earlier in the day

should i drop naltrexone maybe??

day 6 - dosed both at same time after breakfast
dissociation come and goes in waves couple hours in

[PsychoGenesis]

if this doesn't work as expected I'm wondering about trying propanolol + SJW to resensitize 5ht receptors what do you guys think?

or maybe propanolol / ginkgo + glycine? already have those on hand

idea taken from here

https://www.longecity.org/forum/topic/9 ... -and-pssd/

[Jaxx]

i suggest to give the trial a fair chance first, including proper time to evaluate afterwards before trying something new.
thanks for logging it!

[PsychoGenesis]

yeah I'll follow it up to the end, you're welcome

but I'm trying to think ahead which is the culprit in case it doesn't work

7th dose today was 30min ago all at once


yesterday i got quite dissociated like the first days not sure what's happening



EDIT 10PM

no dissociation today with 360mg

[PsychoGenesis]

8th day 200 dxm / 20 naltrexone

tonight i got a surge of an "intuitive posivity" hard to explain
also I'm craving apples

[PsychoGenesis]

had some horny dreams tonight and even got to remember it which is nice

took a dose of nal-tyrosine/citrulline and went to the gym at 10am

then before my 9th dose today at 1:30pm i started feeling tingles on my dick, getting randomly excited(no stimulus)
felt strange and familiar at the same time

Edit
10th day 100 dxm / 10 naltrexone, upon awakening
had nightmares all night long which is not usual, deep sleep only 10min

[PsychoGenesis]

ok last dose today
had nightmares with same theme again
feeling very "normal" sometimes seems like something is sparking up sensitivity wise but is not quite there yet

[Jaxx]

Curious to hear how the next week will go, keep us posted!

[PsychoGenesis]

feeling more sensitivity but is really subtle
cum volume is good and stronger
better orgasm, at least once a day
emotional aspect is a bit worse now with the NMDA rebound losing motivation...but memantine is helping
reading the report from varicocelle-guy i think the best is still to come in the next few days

[DrugsAreBad]

Any memory issues from DXM? (or suggestions on how do avoid them)