BPC-157: a healing peptide

[north4]

https://www.reddit.com/r/Nootropics/com ... _benefits/

https://www.reddit.com/r/Nootropics/com ... nootropic/

https://www.reddit.com/r/Nootropics/com ... rested_in/

http://www.uk-peptides.com/bpc-157-5mg

[north4]

https://www.reddit.com/r/Nootropics/com ... eddamaged/

https://www.reddit.com/r/Nootropics/com ... al_bpc157/

https://www.alibaba.com/trade/search?fs ... viewtype=G

http://www.austropeptide.com/product/bpc-157-10mg/

i will try soon kudzu extract (1:5) ... maybe someone will try this "miracle" ?

[Bigmum]

North.....what about goldstein protocole not cure but sometimes helps
https://sexualmed.org/forums/topic/1335/

[north4]

i try this from dr. bob forum. licorice alone does not cured, but maybe it was
the kudzu root, or synergetic effect ?

Conudrum, hi, although you were quite rude to me, I would like to update you on my success in recovery. My sex drive is getting very strong, also everything else is coming flooding back, Iam 100% at times dropping to 90% at other times, I have been taking LICORICE ROOT FOR A FEW MONTHS, IT TOOK ALMOST 3 MONTHS TO START TO NOTICE CHANGES. I kept telling myself I cannot be damaged these drugs are tested on millions. Also I knew it wasn't just the sex drive, I never got excited, I never got thrilled, I never got scared, goosebumps or heavy sweating. I used to be quite nervous and sweat alot, all this had gone. As we both know norepinephrine plays a massive part, its just about how do we get the adrenal glands working again. LICORICE ROOT ITS THE NEXT BEST THING TO A MIRACLE!!!!!!!!!! I am being 100% serious, thank God, I really thought I was stuck in a life of anhedonia, with no hope. just lay there with no feelings, no enjoyment. Just feeling very flat and cold. But now its back, sorry to be graphic but i feel like my testicles are alive again, i feel very sexual, its like when you are full of adrenaline the testes are filled with life and so is the brain. I think it has to do with adrenaline and noradrenaline. When I am nervous my heart now races once again, I can sleep easily through the night and love my sleep, I also enjoy exercising and being active. This is a gift a gift of the highest order. It is adrenaline and noradrenaline that drives our brains and our bodies. I couldn't not share this. Finally I am pretty sure this is the solid cure for PSSD and Anhedonia. Your brain is fine, you've got adrenal fatigue and LICORICE ROOT SUPPLEMENT is one of the only ways to heal. I'll tell you now if you start taking it you will notice effects, but don't go mad be ve3ry patient. Take no more than one 450mg capsule a day, never take 2. This will gradually ehqal your adrenal glands and you will make a full recovery. Make sure you take for at least 6 months before giving up on it. Also if you are getting anxious and feeling depressed lower the frequency to maybe 5 a week or less, but stick with it low dose, every day, I'ts taken me at least 3 months to get my sex drive back, you may have to endure some anxiety at first, but trust me its worth it. I feel normal and functional again, thank god, I really couldn't go on much longer. Please give it a try, and be very patient expect it could take months to work as its a slow healing process, to see if you will respond ask yourself: do you sweat less? do you feel your heart racing less when you are anxious? do you feel disconnected from your body? do your testes feel dead? do you lack excitement? do you like thrill? do you never feel like going on a run and releasing your energy. If so you almost certainly have some form of adrenal fatigue, that will be all and thank God for Licorice root extract. Also I have taken small quantities of kudzu root to reduce serotonin, but only a small bit, I have taken no medicine for 2 months not a single tablet, I feel sorry for people going through what I've been through. SSRI's + depression = adrenal fatigue, please go and get better. Thanks.
One last note, please ride through the ups and downs of starting licorice root, keep persevering and you will succeed!

[Bigmum]

Look at ....2 months....probably he havent pssd
I

[Kinncrimson]

https://www.reddit.com/r/Nootropics/comments/5raknu/bpc157_a_healing_peptide_summary_of_known_benefits/

https://www.reddit.com/r/Nootropics/com ... nootropic/

https://www.reddit.com/r/Nootropics/com ... rested_in/

http://www.uk-peptides.com/bpc-157-5mg

wow north, great found...

beside the ENDLESS health benefits bpc-157 also decreases 5-ht synthesis in the raphe nucleus and reverses serotonin syndrome:

https://www.ncbi.nlm.nih.gov/pubmed/15531385
Effects of pentadecapeptide BPC157 on regional serotonin synthesis in the rat brain: alpha-methyl-L-tryptophan autoradiographic measurements.
Tohyama Y1, Sikirić P, Diksic M.
Author information

Abstract
A novel pentadecapeptide, BPC157, was recently reported to have a large spectrum of in vivo activities, from anti-ulcer to central action on the brain dopaminergic system. The mechanisms of these actions are not well understood. In this study, the evaluation of the effects of acute and repeated administration of BPC157 on serotonin (5-HT) synthesis in the rat brain is reported. The alpha-[14C]methyl-L-tryptophan (alpha-MTrp) autoradiographic method was used to measure regional 5-HT synthesis rates. In the first series of experiments, a single dose treatment of BPC157 (10 microg/kg) administered intraperitoneally 40 min before the alpha-MTrp tracer injection significantly reduced the regional rate of 5-HT synthesis in the dorsal thalamus, hippocampus, lateral geniculate body and hypothalamus. 5-HT synthesis rates in the substantia nigra reticulate and medial anterior olfactory nucleus in BPC157 treated rats were significantly higher than in the control rats. No significant change in the synthesis rate was observed in the raphe nuclei. In the second series of experiments, following a 7-day treatment with BPC157 (10 microg/kg; s.c.), a significant reduction in the 5-HT synthesis rate was observed in the dorsal raphe nucleus, and significant increases were observed in the substantia nigra, lateral caudate, accumbens nucleus and superior olive. This data suggests that BPC157, a gut peptide, influences brain 5-HT synthesis in rats, but we cannot determine, from this data, the mechanism of this action.

https://www.ncbi.nlm.nih.gov/pubmed/15840402
Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats.
Boban Blagaic A1, Blagaic V, Mirt M, Jelovac N, Dodig G, Rucman R, Petek M, Turkovic B, Anic T, Dubovecak M, Staresinic M, Seiwerth S, Sikiric P.
Author information

Abstract
Serotonin syndrome commonly follows irreversible monoamine oxidase (MAO)-inhibition and subsequent serotonin (5-HT) substrate (in rats with fore paw treading, hind limbs abduction, wet dog shake, hypothermia followed by hyperthermia). A stable gastric pentadecapeptide BPC 157 with very safe profile (inflammatory bowel disease clinical phase II, PL-10, PLD-116, PL-14736, Pliva) reduced the duration of immobility to a greater extent than imipramine, and, given peripherally, has region specific influence on brain 5-HT synthesis (alpha-[14C]methyl-L-tryptophan autoradiographic measurements) in rats, different from any other serotonergic drug. Thereby, we investigate this peptide (10 microg, 10 ng, 10 pg/kg i.p.) in (i) full serotonin syndrome in rat combining pargyline (irreversible MAO-inhibition; 75 mg/kg i.p.) and subsequent L-tryptophan (5-HT precursor; 100 mg/kg i.p.; BPC 157 as a co-treatment), or (ii, iii) using pargyline or L-tryptophan given separately, as a serotonin-substrate with (ii) pargyline (BPC 157 as a 15-min posttreatment) or as a potential serotonin syndrome inductor with (iii) L-tryptophan (BPC 157 as a 15 min-pretreatment). In all experiments, gastric pentadecapeptide BPC 157 contrasts with serotonin-syndrome either (i) presentation (i.e., particularly counteracted) or (ii) initiation (i.e., neither a serotonin substrate (counteraction of pargyline), nor an inductor for serotonin syndrome (no influence on L-tryptophan challenge)). Indicatively, severe serotonin syndrome in pargyline + L-tryptophan rats is considerably inhibited even by lower pentadecapeptide BPC 157 doses regimens (particularly disturbances such as hyperthermia and wet dog shake thought to be related to stimulation of 5-HT2A receptors), while the highest pentadecapeptide dose counteracts mild disturbances present in pargyline rats (mild hypothermia, feeble hind limbs abduction). Thereby, in severe serotonin syndrome, gastric pentadecapeptide BPC 157 (alone, no behavioral or temperature effect) has a beneficial activity, which is likely, particular, and mostly related to a rather specific counteraction of 5-HT2A receptors phenomena.

--------------------------------------------------

Honestly, I don't care anymore, I will try anything and anything to overcome this shit, even though I'm looking foward to Sulawesis PSSD study..... I bought a 4 week cycle of PBC-157 from an Austrian vendor.

I will let you know when I start.

[north4]

http://www.stevenfoster.com/education/m ... orice.html

https://www.researchgate.net/publicatio ... components

https://www.ncbi.nlm.nih.gov/pubmed/?te ... +uralensis https://www.ncbi.nlm.nih.gov/pubmed/?te ... iza+glabra

---

Kudzu: https://www.ncbi.nlm.nih.gov/pubmed/?te ... ria+lobata

----

https://www.ncbi.nlm.nih.gov/pubmed/?te ... gistic+tcm

[Kinncrimson]

Tried BPC-157 for 21 days @ 500 mcg..... Did nothing.

[jaiho]

I'm going to try this stuff, sounds really interesting for anhedonia symptoms.
Even if it doesn't work, its good to have around if you ever get an injury, the healing effects are remarkable by reports.

[Bigmum]

It helped you GIXXER? or PT 141?