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Re: Delving into the sex hormones connection

Unread postPosted: Thu Aug 01, 2019 1:00 pm
by piwomocne
Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now

Re: Delving into the sex hormones connection

Unread postPosted: Fri Aug 02, 2019 3:06 am
by PsychoGenesis
piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now

next week if everything goes well

Re: Delving into the sex hormones connection

Unread postPosted: Fri Aug 02, 2019 5:19 am
by piwomocne
What dosage u planning to do and for how long
PsychoGenesis wrote:
piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now

next week if everything goes well

Re: Delving into the sex hormones connection

Unread postPosted: Mon Aug 05, 2019 9:12 pm
by PsychoGenesis
[500-600/wk for 4-6 weeks

today is the second day

Re: Delving into the sex hormones connection

Unread postPosted: Tue Aug 06, 2019 5:50 am
by piwomocne
Okey so u only tske nandorolane ore u take finastride too ?

Re: Delving into the sex hormones connection

Unread postPosted: Fri Aug 16, 2019 7:13 pm
by PsychoGenesis
taking nandrolone only on this round, first few days i got furious libido / blood filled my dick all day and i masturbated in a day more than the last 2-3 months


mind you i was on testosterone before