Update:
Ive currently titrated up to 10mg memantine and am planning on going up to the full 20mg dosage before introducing anything else. I took it slow starting at 2.5 the first week then moving up to 5 for a week and now 10mg This week. Because of taking it slow side effects has been minimal in severity and i have felt slight sporadic reliefs in some symptoms (mainly anhedonia) during this time where i have noticed increased hunger and pleasure to food as well as slight pleasure to music, socializing and ability to laugh. This has only been in small sporadic spurts tho and not in any big way. It seems that these effects are most notable during titration and once Ive stabalized on one dosage it goes away. It feels like What is happening is that my altered homeostasis (pssd) gets temporarily «nudged» because of the change introduced to the brain (in This case memantine titration) But it fights back and quickly takes control again. This seems to be the thing with most substances that i have ever felt a slight response to; it works a bit in the beginning But quickly fades. Sometimes i only get brought out of the fog for a few hours before i Get stuck back in pssd limbo. Its a neverending battle.
Anyway i also want to mention that i ordered a few tablets of flibanserin to try out once i have stabalized on memantine.
After stabalizing on 20mg memantine i plan on introduce the following meds;
- Baclofen 12.5/25mg
- Rasagiline (0.25-0.50?)
I would also like to try cyproheptadine and rivastigmine after reading mesolimbos anecdotes.
Current remigen:
- Memantine 10mg
- LDN 3mg
- Seroquel 25mg
- Pregabalin 150mg prn
I have decided to try and log my progress symptomswise from now on to give a more clear picture of my progress and which areas needs more improvements.
These are the specific symptoms i want to adress:
Cognitive dysfunction:
* Depersonalization and derealization
* Brain fog/mental clearity
* Focus and attention
* Memory
* Verbal fluency and Word recall (also including the ability to speak properly and react naturally to conversations without blank mind)
* Loss of creativity
Current function: 20%
Anhedonia:
* Anticipatory: Motivation and drive to do activities that is supposed to bring pleasure
* Consummatory: Pleasure from activities such as socializing, gaming, tv, music, food, excercise
*Responsiveness to pleasurable substances like alcohol and drugs
Current function: 5%
Emotional range and expression:
Emotional blunting:
* Ability to feel emotions
* Empathy
Blunted/flat affect:
* Inability to cry and laugh
* Inability to connect with others
* Natural reactions to the environment without having to fake it
Current function: 0%
Sexual dysfunction:
* Libido
* Physical and mental attraction
* Erectile dysfunction
* Anorgasmia
* Genital anesthesia
* Premature ejaculation
Current function: 10%
General physical symptoms:
* Chronic fatigue
* Muscle weakness
* Lack of sensations (including diminished taste, smell, skin sensitivity)
* Various muscle stiffness and pain
* GI issues (IBS)
Current function: 25%
I will update this post later to give a percentage of Where i feel i am at with each symptom to track progress.
Edit: updated %.