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Vardenafil & Sildenafil

Unread postPosted: Fri Oct 20, 2017 9:48 am
by Numbed
Why has this never been posted anyway, people are sleeping under a rock here???

Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe

Vardenafil Enhances Oxytocin Expression in the Paraventricular Nucleus without Sexual Stimulation

Vardenafil Reversal of Female Anorgasmia ... 61.11.2133

Vardenafil reverses erectile dysfunction induced by paroxetine
in rats

Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil.

Someone who has good knowledge explain if this would be beneficial or not especially the effect on 5htp levels, would vardenafil increase or lower serotonin levels?
Also im 70% recovered by using ginkgo and cdp-choline, not 100% yet, but I feel as if my brain is normalizing.
Ran out of inositol weeks ago so adding that back again to finally use them all 3 together, my hope is 85-90% recovery by the addition of inositol.

Re: Vardenafil & Sildenafil

Unread postPosted: Fri Oct 20, 2017 12:31 pm
by Pep19
Do you take a vardenafil or sildenafil, or together?
Every day?
I would like to try a inositol, I take a sildenafil or tadalafil, the erection is good but my libido isn't good.
Cialis 5mg every day for 3 months it can reestablish erection definitively?

Re: Vardenafil & Sildenafil

Unread postPosted: Sat Oct 21, 2017 6:13 am
by Numbed
Ive only seen studies of sildenafil and vardenafil having an oxytocin like mood/brain effects.

Cialis seems to not do this (atleast didnt found any studies when searching online), cialis most likely also targets different isoenzymes of PDE's.

And no I do not take vardenafil nor sildenafil daily though on times I do take it, there is definatly some sexual enhancement mentally going on, not just increased sensitivity downstairs.
Especially vardenafil looks promising, im currently re-introducing inositol back again and expecting to get benefits from it once again. After that I'll reconsider if I want to do the daily vardenafil dosing.

I dont get most of the guys on here anyway, seems alot of them are 'scared' to get detoriations of their none existant libidos? I mean come on if you got nothing to lose go all in and try everything that cause possibly benefit you.
Then again my libido issues seemed to come 100% from my brain, my testosterone levels came back good.

Re: Vardenafil & Sildenafil

Unread postPosted: Wed Nov 01, 2017 5:34 pm
by alteredhomeostasis
Numbed thanks for posting this. This is the post that got me to take the cialis my psych prescribed and it has been a great move. I'm taking 2.5 every other day and I'm getting good morning wood and am able to perform a lot better sexually. This has been good psychologically. Other symptoms remain but this helps a lot.

reading some of the posts of those who recovered, it seems like at least a couple of them were using cialis to manage their symptoms. It seems possible that cialis could be helpful to recovery from a pharmacologic perspective, rather than solely psychologically.

Otherwise, since taking the cialis, I'm definitely sleeping a lot better. My sheets are comfy as fuck in the morning.

Re: Vardenafil & Sildenafil

Unread postPosted: Thu Nov 02, 2017 4:34 am
by Numbed
Not a prob,

I feel as if viagra still gives the strongest oxytocic boost out of all 3 of them, cialis is weird, gives me unwanted boners without the desire, its odd and annoys me.
Cialis also inhibits pde11 from what I understand, and pde11 ACTIVATION is necesarry for normal response to social cues in animal models.

Im assuming you have been taking 2.5mg vardenafil btw or???