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Re: PSSD Genome Project [Megathread]

Unread postPosted: Fri Mar 22, 2019 5:50 pm
by GIXXER
I did some DNA pharmacogenomic testing with a company here in Canada. It basically takes out the trail and error process of these meds based on our genotypes. Today I received my results. Its very in depth for my genotype and recognized that my genes don't react well with SNRI/SSRI. Some recommendations were made on what will work for me. Im not sure if I will follow them yet as all these meds terrify me.

Also a med called Brexpiprazole came up in my report.

Brexpiprazole, sold under the brand name Rexulti, is an atypical antipsychotic. It is a dopamine D2 receptor partial agonist and has been described as a "serotonin–dopamine activity modulator" (SDAM).

Re: PSSD Genome Project [Megathread]

Unread postPosted: Wed Apr 17, 2019 2:50 pm
by Ghost
@Mesolimbo
When using the charts remember that:
C = RED
G = GREEN
A = BLUE
T = BLACK
Heterozygotes will be combinations of the above colors.


5HTTPLR allele
- rs25531 (irrelevant on 23+Me apparently - all are called C/C)
- rs25532:
-- 4 SNPs for rs25532 analyzed for frequency --
CC: 0.0
CG: 0.0
GG: 50.0
AA: 0.0
AT: 0.0
TT: 0.0
CT: 0.0
AG: 50.0
AC: 0.0
GT: 0.0
CHART (Click to open):
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0

- rs2129785:
-- 28 SNPs for rs2129785 analyzed for frequency --
CC: 0.0
CG: 0.0
GG: 0.0
AA: 0.0
AT: 0.0
TT: 85.71428571428571
CT: 14.285714285714285
AG: 0.0
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0

- rs11867581:
-- 29 SNPs for rs11867581 analyzed for frequency --
CC: 0.0
CG: 0.0
GG: 13.793103448275861
AA: 37.93103448275862
AT: 0.0
TT: 0.0
CT: 0.0
AG: 48.275862068965516
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0
--------------------------------------------------------------------------------------------------------
COMT-Met
- rs4680:
-- 29 SNPs for rs4680 analyzed for frequency --
CC: 0.0
CG: 0.0
GG: 27.586206896551722
AA: 20.689655172413794
AT: 0.0
TT: 0.0
CT: 0.0
AG: 51.724137931034484
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0

- rs4633:
-- 28 SNPs for rs4633 analyzed for frequency --
CC: 25.0
CG: 0.0
GG: 0.0
AA: 0.0
AT: 0.0
TT: 21.428571428571427
CT: 53.57142857142857
AG: 0.0
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0

- rs165599:
-- 29 SNPs for rs165599 analyzed for frequency --
CC: 0.0
CG: 0.0
GG: 6.896551724137931
AA: 31.03448275862069
AT: 0.0
TT: 0.0
CT: 0.0
AG: 62.06896551724138
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0
--------------------------------------------------------------------------------------------------------
FKBP5:
- rs1360780
-- 28 SNPs for rs1360780 analyzed for frequency --
CC: 57.14285714285714
CG: 0.0
GG: 0.0
AA: 0.0
AT: 0.0
TT: 14.285714285714285
CT: 28.57142857142857
AG: 0.0
AC: 0.0
GT: 0.0
https://chart.apis.google.com/chart?cht ... ,1,0|1,1,0

Re: PSSD Genome Project [Megathread]

Unread postPosted: Mon Jul 15, 2019 12:52 am
by Ghost
I will be starting another iteration of the genome project in the coming weeks.

My computer suddenly crashed this spring and with it I lost a lot of the organization I had with the genome project. I still have copies of all of the genomes, but I either need to find a way to recover some of my scripts and reorganize the data, or do it again - which would take a lot of time.

I'm building a new computer this week and after that will give some updates on how the project is progressing.

Stay tuned.