J Sex Marital Ther. 2019 Jan 14:1-7. doi: 10.1080/0092623X.2018.1556755. [Epub ahead of print]
Towards improving post-SSRI sexual dysfunction by using nutriceuticals: Lessons from a case study.
Salvatore Calabrò R1, De Luca R1, Manuli A1, Portaro S1, Naro A1, Quattrini F2.
Author information
1 a IRCCS Centro Neurolesi "Bonino-Pulejo" , Messina , Italy .
2 b DISCAB, University of L'Aquila , L'Aquila , Italy.
Abstract
Post-selective serotonin reuptake inhibitors (SSRIs) sexual dysfunction (PSSD) is a new clinical entity occurring after the antidepressant intake, and it is characterized by the fact that patients continue to present sexual side effects after the discontinuation of the drugs. PSSD mainly consists of hypo-anesthesia of the genital area, loss of libido, and erectile dysfunction. Although different management options have been proposed, there is no consensus on the treatment for this syndrome. Herein we report on a young man affected by PSSD who regained sexual functioning after 3-month treatment with EDOVIS, a dietary supplement containing L-citrulline and other commonly used aphrodisiacs. Clinicians should be aware about the possibility of persistent sexual side effects induced by serotoninergic antidepressants and take into considerations the use of nutraceuticals to overcome PSSD.
KEYWORDS:
L-citrulline; SSRI; dietary supplements; iatrogenic sexual dysfunction
PMID: 30640584 DOI: 10.1080/0092623X.2018.1556755
https://www.ncbi.nlm.nih.gov/pubmed/30640584