Who has tried ropinirole?

[Micromegas]

If you have tried ropinirole (Requip), please share your experience. The only person I've seen talk about using it is Sonny.

I've read the reviews on askapatient.com from people who've used it for RLS and Parkinson's, and a lot of men mention higher libido and more erections as side effects, so that's promising.

This is the next thing on the list for me, and I'd like to hear other people's feedback.

[Micromegas]

Thanks for the reply. Did you try it specifically for PSSD? I've put off using a dopamine agonist for a couple years now because of being wary of them, but I've tried several other things with little results. The only thing I've found that makes a substantial difference for me is Cialis, and I really need to find something that will benefit the brain aspect of the problem (as in libido/arousal) similar to the way Cialis helps the erection aspect. In other words, Cialis helps with erections, but my brain will hardly send the signal to make them happen. So I really want to address that problem, and dopamine agonists seem like my best bet at this point. I'd be glad to hear anyone's suggestions or opinions.

[IHateProzac]

If you have tried ropinirole (Requip), please share your experience. The only person I've seen talk about using it is Sonny.

I've read the reviews on askapatient.com from people who've used it for RLS and Parkinson's, and a lot of men mention higher libido and more erections as side effects, so that's promising.

This is the next thing on the list for me, and I'd like to hear other people's feedback.

I take it now & then. On its own it does 'little to nothing much' for me. But combined with Viagra it gives good response. I haven't felt high libido let alone hyper sexual on it, however it does induce some degree of pleasure.

I talked with a neurologist before starting Requip. He said its generally harmless & safe to take it around 0.75mg (1+1+1) to 1.5mg/2mg (1+1+1) a day. He prescribed the dosage for 6 weeks. If it doesn't work then no need continuing it. I on the other hand usually avoid Requip now days because even though it increases my semen volume (5.5 to 7 ml) it usually makes it thin & watery.

Also keep in mind that Requip can stimulate your anxiety & depression slightly.

[forexworld12]

If you have tried ropinirole (Requip), please share your experience. The only person I've seen talk about using it is Sonny.

I've read the reviews on askapatient.com from people who've used it for RLS and Parkinson's, and a lot of men mention higher libido and more erections as side effects, so that's promising.

This is the next thing on the list for me, and I'd like to hear other people's feedback.

I take it now & then. On its own it does 'little to nothing much' for me. But combined with Viagra it gives good response. I haven't felt high libido let alone hyper sexual on it, however it does induce some degree of pleasure.

I talked with a neurologist before starting Requip. He said its generally harmless & safe to take it around 0.75mg (1+1+1) to 1.5mg/2mg (1+1+1) a day. He prescribed the dosage for 6 weeks. If it doesn't work then no need continuing it. I on the other hand usually avoid Requip now days because even though it increases my semen volume (5.5 to 7 ml) it usually makes it thin & watery.

Also keep in mind that Requip can stimulate your anxiety & depression slightly.

well, requip is very effective to reverse ssri induced anhedonic depression. It effectively enables real emotion ..
http://www.degruyter.com/view/j/jbcpp.2 ... 11.027.xml
http://www.ncbi.nlm.nih.gov/pubmed/17187269

But if you read this report here - http://www.ncbi.nlm.nih.gov/pubmed/12409684.

you'll see it's not very effective for ssri induced sexual dysfunction with a success rate of 54% ... basically a dopamine agonist is not going to do much if serotonin is all over the place

Overall based on my re-search I'll say ropinirole is the most "safest" out of all the dopamine agonists it's less likely to mess up things that the other agonist .

[IHateProzac]

As for as I have noticed so far the researches/studies on Requip's ability to reverse PSSD are either preliminary, incomplete or inconclusive. Don't get me wrong, but people I have talked with who have used Requip have not suggested the same or similar outcome that these researches suggest. There are mixed reactions in general. I myself have been using Requip & have not noticed anything dramatic.

[Micromegas]

Thanks guys, I really appreciate everyone's feedback.

On its own it does 'little to nothing much' for me. But combined with Viagra it gives good response.

I was thinking this might be a realistic expectation. Naturally there's a part of me that hopes everything I try will be a silver bullet and fix everything, but at this point I'm pretty sure it's going to take a stack to do anything major.

If I try it and it doesn't work out, I guess I'll be looking at cabergoline next, maybe pramipexole at some point.

be wary of daws, though, and anhedonia. that, and again, mental illness risks associated with dopamine agonists, particularly if you are predisposed

This also bugs me. I also have some tendency toward anxiety and OCD, so I'll definitely watch out for those.

well, requip is very effective to reverse ssri induced anhedonic depression. It effectively enables real emotion ..
http://www.degruyter.com/view/j/jbcpp.2 ... 11.027.xml
http://www.ncbi.nlm.nih.gov/pubmed/17187269

But if you read this report here - http://www.ncbi.nlm.nih.gov/pubmed/12409684.

you'll see it's not very effective for ssri induced sexual dysfunction with a success rate of 54% ... basically a dopamine agonist is not going to do much if serotonin is all over the place

Thanks for the links. I've thought about the serotonin thing possibly being an issue with these. Similarly, I figure low dopamine is partially why bupropion has little prosexual effect for me.

I myself have been using Requip & have not noticed anything dramatic.

What dose have you been using?

[IHateProzac]

I myself have been using Requip & have not noticed anything dramatic.

What dose have you been using?

Began with .75mg then got prescription for 1.5mg per day. But haven't gotten around to taking the 1.5 dosage. In fact I stopped taking Requip as it makes my semen watery.

[forexworld12]

Yes I was talking about people who are anhedonic from ssri use . DA's reverses anhedonia in them but true I do not recommend DA's at all to anyone .. as you mentioned they can cause problem of their own and they also have the potential to cause severe anhedonia ... the worst of them is Mirapex(pramipexole) followed by cabergoline .....if i ever have to take a da it would only be ropinirole ..

Since DA's can cause downregulation/desensitization of dopamine receptor one with PSSD would now have double trouble to fix as you mentioned...

[Ghost]

well, requip is very effective to reverse ssri induced anhedonic depression. It effectively enables real emotion ..
http://www.degruyter.com/view/j/jbcpp.2 ... 11.027.xml
http://www.ncbi.nlm.nih.gov/pubmed/17187269

in the short term, although i'd like to know what longer-term studies show. i would think that many if not most people who are not suffering from, say, parkinson's disease, would become terribly anhedonic on the dopamine agonists when they are taken long-term due to down regulation and such.

these study's findings support this notion, albeit with lab rats and not humans --
http://www.ncbi.nlm.nih.gov/pubmed/8101360
http://www.biomedcentral.com/1741-7007/2/22

tangentially supporting this idea are the findings that "l-dopa reverses the elevated density of d2 dopamine receptors in parkinson's diseased striatum."
http://link.springer.com/article/10.100 ... 971#page-1

additionally, anecdotal reports across the net have some reporting anhedonia with continued, long-term use of the da agonists. dopamine agonist withdrawal syndrome is reportedly very difficult as well.

anyhow, i'm not trying to persuade anyone not to take the drugs, but rather to make informed decisions as one person's savior drug is another person's worst nightmare -- case in point: the ssris.

Couldn't agree more. I have friends who swear by SSRI's, but it doesn't mean that they will help me.

[Sonny]

For fuck sakes forex. I have 0 patients for you. NONE. Knock it the fuck off. First warning, last warning, only thing I'm fucking saying. I'm entirely too busy to deal with some petulant child spouting off nonsense and being a pain people's asses. Now lets stop with this shit. I'm not anyone's father, and I don't do babysitting. Quite frankly I've seen a lot of downright disappointing behavior.