I don't have PSSD but....

[iull1k]

My theory is the SSRIs, when taken for a long term, are first of all creating "the ground for PSSD" by inducing persistent brain changes, probably on microarchitectural - dendritic / axons level. Then you are starting to be susceptible to get PSSD on any occasion, you need just inducing agent which brings PSSD from it's non-active state to active state. This may be SSRI itself, An atypical Antidepressant, a neuroleptic, a mood stabilizer, or even high stress. You suddenly, "out of nowhere" get emotionally blunted, asexual and your genitals, or whole body starts to be anaesthetised.

This may explain why people who have used SSRI extensively before, get PSSD after abrupt withdrawal or when they've switched to an another drug.

I've taken clomipramine myself for 6 months almost without AE, felt some emotional blunting at the end which let me to go cold turkey. The anxiety was coming back, so short after, I started the escitalopram only to get a sudden lobotomy-like emotional blunting and full sexual dysfunction with anaesthesia after just 3 days of use. The symptoms are continuously present to this day, almost 6 years has passed

How are you doing with imagination, logical thinking, attention, abstract thinking? Thank you

[tigerbloodforever]

Absolutely take a couple of T shots. I believe that correcting the hormone imbalance is the first step in getting better. They will not get you better by themselves but you need to stop the endocrine crashes before you do anything with your recovery. See my website for more details.

http://www.5arinhibitorhelp.com/progress/

[tigerbloodforever]

I absolutely believe that a couple of T shots are necessary to start your recovery. They will not recover you completely but the will stop the crashes from happening which is the first step of the recovery, Check out my website for more info.

http://www.5arinhibitorhelp.com/progress/

[berserker]

At the moment I am under medication. My hope is that it will get better once I taper them....this is really stuff of nightmares

[berserker]

So, a little updated. I managed to taper Anafranil from 150mgs daily to 75mgs. I quit mirt and tapered Zyprexa from 5 mgs daily to 2,5 mgs. My days are still confusing. I tend to obsess over my lack of libido and test if my 'thingy' works. It does but with a lot of struggle. I don't get spontaneous erections (only some during sleep), watery sperm and getting 'there' manually is a struggle. I will most likely be meds free in about a month.....then it will be waiting time. I have been taking inositol for the last 3 days. Would be possible that I regain my libido after some time being clean? I lost it after 9 years of anafranil use...I feel like being in a bad nightmare. It was something so natural that when you loose it all seems so strange and unreal. I used to fantasise a lot about women...

[berserker]

I think I should change the subject of this thread. I come to the conclusion that I really have pssd. This month has been REALLY difficult for me. I suffer from OCD and obviously I obsess about my condition. I tapered anafranil and I am still having big withdrawal symptoms...anxiety, suicidal thoughts, insomnia, akathisia and so on. I had to do something about it. So it's has been a few days that I have been taking zyprexa to calm me down. A week ago I was still able to masturbate. Today nothing happens...like really NOTHING. I am lost at what to do. My relatives don't really understand what's going on and would like me to go back on ADs but that would mean to lessen every possibility of recovery. I think my case is a little different from what I read here. I don't have genital numbness but zero libido and (at the moment) no way to have an erection. It's like touching a rubber band...I am really lost at what to do.

[drew]

I suffer from PSSD too. My testosterone levels are of an 80 year old. My libido is dead and getting aroused is not possible. I wonder if this idea will work for me. I'm on a testosterone boosting supplement for body builders based on zinc, DHEA, boron, DAA, Rhodiola crenulata(Over the counter) These supplements have to be cycled (on 5 days, off 2 days) since it involves kick-starting testosterone. If I don't, I risk HPTA shutdown (similar to PSSD symptoms but a double whammy this time if not careful. Over masturbation can also cause HPTA Lock since the adrenals are exhausted from over masturbation so no trying to "see if it works "per se)I'm going to stay on supplementing for 2 months. The side effect of these boosters is a strong libido so we'll see how it shakes out. I am seeing more "windows" (improvements) especially when cycling off. I wonder if this little formula might cycle me out of PSSD.... Hormones are a delicate feedback cycle in the HPT axis.. It seems somehow SSRI's affect it. My T levels are low.. 406 low and I'm mid 30's.