PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect
with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs
with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)
5ar likely becomes upregulated also
then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself
we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression
going to try it after the testosterone trial im doing now