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Delving into the sex hormones connection

This is for hypothesis and even educated speculation.

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First unread post • 26 posts • Page 3 of 3 • 1, 2, 3

Re: Delving into the sex hormones connection

Unread postby piwomocne » Thu Aug 01, 2019 1:00 pm

Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now
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Re: Delving into the sex hormones connection

Unread postby PsychoGenesis » Fri Aug 02, 2019 3:06 am

piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now

next week if everything goes well
PsychoGenesis
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Re: Delving into the sex hormones connection

Unread postby piwomocne » Fri Aug 02, 2019 5:19 am

What dosage u planning to do and for how long
PsychoGenesis wrote:
piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now

next week if everything goes well
piwomocne
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Posts: 118
Joined: Mon Aug 21, 2017 2:41 pm
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Re: Delving into the sex hormones connection

Unread postby PsychoGenesis » Mon Aug 05, 2019 9:12 pm

[500-600/wk for 4-6 weeks

today is the second day
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Re: Delving into the sex hormones connection

Unread postby piwomocne » Tue Aug 06, 2019 5:50 am

Okey so u only tske nandorolane ore u take finastride too ?
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Re: Delving into the sex hormones connection

Unread postby PsychoGenesis » Fri Aug 16, 2019 7:13 pm

taking nandrolone only on this round, first few days i got furious libido / blood filled my dick all day and i masturbated in a day more than the last 2-3 months


mind you i was on testosterone before
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