Topic: https://raypeatforum.com/community/thre ... nes.12571/
Symptom list:
Dubya_B wrote:Hello. Wanted to chime-in here and say that I have a close acquaintance with MS. We were discussing our respective conditions and our mental/neurological symptoms are strikingly similar, although hers sound as if they are much milder. ...Perhaps she is just more accepting of it. Emotional blunting, anhedonia, depression, personality changes, and memory problems are something we both deal with. I can see it in her that she is one of the most un-emotional people I know, next to myself.
I chalked this up to the neurosteroid deficiency in MS patients, that was recently discovered to be a severe deficiency in PFS patients, and making the assumption the same applies to PAS and PSSD.
An article discussing high levels of 5-ar-1-silencing miRNA and decreased levels of neurosteroids in MS patients:
http://brain.oxfordjournals.org/content/134/9/2703
The PFS neurosteroid study:
https://www.sciencedirect.com/science/article/abs/pii/S0960076017301024
She doesn't really have sexual dysfunction, outside of what comes along with emotional bluntness and anhedonia, but has mild balance and coordination problems, as you mention.
I'm eager to see how the allopregnanolone precursor drug (SAGE-217) effects us if/when it is made available as a depression treatment.
https://en.wikipedia.org/wiki/SAGE-217
Dubya_B wrote:That's very concerning if this is progressively getting worse for you. They also sound like very severe neurological symptoms of PSSD/post-SSRI. Have you been checked for MS lesions for the sake of ruling it out? There is always the slim chance development of MS with a manifestation of some sexual symptoms coincided with SSRI use. Not sure which is worse though. MS is at least treatable in many cases.
Users browsing this forum: Distortion, Google [Bot] and 1 guest